June 8, 2016

Applying Stem Cell Therapy to Treat Crohn’s Disease

By Lindsey Kirkeby

As seen in "Inside Mayo Clinic Research"

Promising Application for Stem Cells: Crohn's Complications

New research at Mayo Clinic is bringing hope to hundreds of thousands of Crohn’s disease patients. Their extreme pain from complications is both physical and emotional and, for many, incurable. But, an innovation using the patient’s own stem cells seems to work extremely well in early testing. Eventually, researchers say, it may be used to treat Crohn’s disease in general.

In this video, “Another Promising Application for Stem Cells: Crohn's Complications,” the Mayo Clinic team of Allan Dietz, Ph.D., Eric Dozois, M.D., and William Faubion, M.D., discuss their work using stem cell therapy to treat Crohn’s disease.

Although this phase I clinical trial is still underway, and final results are not yet available, the vast majority of patients’ fistulas have healed completely. The same research team is also investigating how to use this process to treat other nonhealing fistulas and Crohn’s disease as a whole.

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